Methicillin-resistant staphylococci: genetics and mechanisms of resistance

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Methicillin-resistant staphylococci.

Strains of staphylococci resistant to methicillin were identified immediately after introduction of this drug. Methicillin-resistant strains have unusual properties, the most notable of which is extreme variability in expression of the resistance trait. The conditions associated with this heterogeneous expression of resistance are described. Methicillin resistance is associated with production ...

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Methicillin-resistant staphylococci.

Eighteen strains of Staph. pyogenes (nine penicillin-sensitive and nine penicillin-destroying) were passaged 40 to 50 times on Celbenin(1) ditch plates. All strains developed an increase in resistance to Celbenin and eight strains (four penicillin-sensitive and four penicillin-destroying) were able to grow in 100 mug/ml. or more Celbenin. Resistance was of the drug-tolerant type and none of the...

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Characteristics of Methicillin-resistant Staphylococci.

Sutherland, R. (Beecham Research Laboratories Ltd., Betchworth, Surrey, England), and G. N. Rolinson. Characteristics of methicillin-resistant staphylococci. J. Bacteriol. 87:887-899. 1964.-Cultures of naturally occurring methicillin-resistant staphylococci obtained from a number of hospitals were examined for the nature and degree of resistance to methicillin and other antibiotics. All the cul...

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Methicillin-resistant Staphylococci and Hospital Infection.

AYLIFFE, G. A. J., and BARBER, M. (1963): Brit. med. J., ii, 202. BARBER, M. (1961): J. clin. Path., 14, 385. BARBER, M. (1962): In "Resistance of Bacteria to the Penicillins" (edited by A. V. S. de Reuck and M. P. Cameron), p. 89. London: J. & A. Churchill. BoRowsKI, J., KAMIENSKA, K., and RUTECKA, I. (1964): Brit. med. J., i, 983. CETIN, E. T., and ANG, 0. (1962): New Istanbul Contr. clin. Sc...

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Prevalence of Methicillin-Resistant Staphylococci in Dogs

The aim of the study was to investigate the occurence and species distribution of methicillin resistant staphylococci (MRS) in the nasal cavity of dogs. Nasal swabs were collected from 162 dogs entering private veterinary clinics in Hatay. Methicillin resistance was detected onto mannitol salt agar containing 2 μg/ml oxacillin and confirmed by mecA Polymerase Chain Reaction (PCR). Bacterial ide...

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ژورنال

عنوان ژورنال: Antimicrobial Agents and Chemotherapy

سال: 1989

ISSN: 0066-4804,1098-6596

DOI: 10.1128/aac.33.7.991